Comment of the Network of Coordinating Centers for Clinical Trials (KKS-Network), Germany on the Concept Paper Submitted for Public Consultation on 09/02/2011 Revision of the Clinical Trials Directive 2001/20/EC

ENCEPP CONSIDERATIONS ON THE DEFINITION OF NON-INTERVENTIONAL TRIALS UNDER THE CURRENT LEGISLATIVE FRAMEWORK (“CLINICAL TRIALS DIRECTIVE” 2001/20/EC) Agreed by the European Network of Centres for Pharmacoepidemiology

Clinical efficacy of local injection therapies for lateral epicondylitis: A systematic review and network meta-analysis

Background: We aimed to compare the efficacy of local injection therapies for lateral epicondylitis in a Bayesian framework. Methods: We searched the Embase, PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, and ProQuest, for randomized controlled trials published from inception to February 2021 in any languages. The injection therapies included corticosteroids (C...

Tenecteplase versus reteplase in acute myocardial infarction: A network meta-analysis of randomized clinical trials

Background: Acute myocardial infarction (AMI) is the leading cause of death throughout the world. One of the standard approaches to treatment of AMI is fibrinolysis. The study was conducted to evaluate the clinical efficacy of tenecteplase versus reteplase through network meta-analysis for AMI. Methods: Randomized trials were comprehensively searched in PubMed, Scopus, Cochrane library, a...

O-18: Framework of Informed Consent and Ethical Codes for Clinical Trials Especially Designed for Assisted Reproduction

Background Clinical trials are known as the most valid medical research. It is able to promote medical evidences on prevention, diagnosis, screening, treatment, and quality of life because in this type of study, an intervention is intentionally performed on subjects. Therefore, it encompasses ethical concerns and considerations, especially when human subjects are studied. In other words, clinic...

Medicinal plants for gingivitis: a review of clinical trials

Objective(s): Periodontal diseases are among prevalent oral health problems which may ultimately lead to severe complications in oral cavity. Herbal products can be designed as single or multicomponent preparations for better oral health. This study aims to review current clinical trials on the effectiveness of herbal products in gingivitis. Materials and Methods: Electronic databases, includin...